Hopper H200 SXM vs Instinct MI300X
Complete side-by-side comparison of specs, performance, memory, power efficiency, and pricing.
Hopper H200 SXM
74
Spec Wins
Instinct MI300X
65
Detailed Specifications
Hopper H200 SXM — Best For
Instinct MI300X — Best For
Who Should Choose Each GPU?
Choose Hopper H200 SXM if you…
- ✓Need maximum CUDA/TensorRT/vLLM ecosystem compatibility
- ✓Prioritize raw FP8 throughput (3,958 vs 2,614 TFLOPS)
- ✓Have power-constrained data centers (700W vs 750W TDP)
- ✓Running LLM Inference workloads
- ✓Running Large Models workloads
Choose Instinct MI300X if you…
- ✓Need more VRAM (192GB vs 141GB) for large model inference
- ✓Working with a tighter CapEx budget (lower list price)
- ✓Running Large Models workloads
- ✓Running Cost-Effective Training workloads
Verdict
The Hopper H200 SXM and Instinct MI300X target different priorities. The Instinct MI300X's 192GB of HBM3 gives it a clear edge for large-model inference where fitting the full model in VRAM eliminates quantization overhead. For training throughput, the Hopper H200 SXM's 3,958 FP8 TFLOPS outpaces the Instinct MI300X's 2,614 TFLOPS. Teams already invested in the NVIDIA/CUDA ecosystem will have less friction with the Hopper H200 SXM, while teams open to ROCM can benefit from the Instinct MI300X's advantages. Use our TCO Calculator to model the full 3-year cost difference for your specific utilization and power costs.
Hopper H200 SXM vs Instinct MI300X: Common Questions
Which is faster, Hopper H200 SXM or Instinct MI300X?+
In FP8 throughput, the Hopper H200 SXM leads with 3,958 TFLOPS vs 2,614 TFLOPS. For LLM inference, memory capacity and bandwidth often matter more than raw TFLOPS — the Instinct MI300X has more VRAM (192GB).
Is Hopper H200 SXM or Instinct MI300X better for LLM training?+
For LLM training at scale, the Hopper H200 SXM has higher raw throughput. However, the choice also depends on your software stack: Hopper H200 SXM offers CUDA compatibility with the widest framework support (PyTorch, JAX, TensorRT).
What is the price difference between Hopper H200 SXM and Instinct MI300X?+
The Hopper H200 SXM is estimated at $30,000 per unit and the Instinct MI300X at $15,000. Actual pricing varies by vendor, volume, and configuration. Check our Buy page for current reseller pricing.
Which GPU is more power efficient, Hopper H200 SXM or Instinct MI300X?+
The Hopper H200 SXM has a lower TDP (700W vs 750W). Performance-per-watt depends on your workload — for FP8 inference, divide TFLOPS by TDP: Hopper H200 SXM = 5.7 TFLOPS/W vs Instinct MI300X = 3.5 TFLOPS/W.