Hopper H200 SXM vs Instinct MI355X
Complete side-by-side comparison of specs, performance, memory, power efficiency, and pricing.
Hopper H200 SXM
74
Spec Wins
Instinct MI355X
96
Detailed Specifications
Hopper H200 SXM — Best For
Instinct MI355X — Best For
Who Should Choose Each GPU?
Choose Hopper H200 SXM if you…
- ✓Need maximum CUDA/TensorRT/vLLM ecosystem compatibility
- ✓Have power-constrained data centers (700W vs 1400W TDP)
- ✓Running LLM Inference workloads
- ✓Running Large Models workloads
Choose Instinct MI355X if you…
- ✓Need more VRAM (288GB vs 141GB) for large model inference
- ✓Prioritize raw FP8 throughput (4,625 vs 3,958 TFLOPS)
- ✓Running LLM Training workloads
- ✓Running Frontier AI workloads
- ✓Running HPC workloads
Verdict
The Hopper H200 SXM and Instinct MI355X target different priorities. The Instinct MI355X's 288GB of HBM3e gives it a clear edge for large-model inference where fitting the full model in VRAM eliminates quantization overhead. For training throughput, the Instinct MI355X's 4,625 FP8 TFLOPS outpaces the Hopper H200 SXM's 3,958 TFLOPS. Teams already invested in the NVIDIA/CUDA ecosystem will have less friction with the Hopper H200 SXM, while teams open to ROCM can benefit from the Instinct MI355X's advantages. Use our TCO Calculator to model the full 3-year cost difference for your specific utilization and power costs.
Hopper H200 SXM vs Instinct MI355X: Common Questions
Which is faster, Hopper H200 SXM or Instinct MI355X?+
In FP8 throughput, the Instinct MI355X leads with 4,625 TFLOPS vs 3,958 TFLOPS. For LLM inference, memory capacity and bandwidth often matter more than raw TFLOPS — the Instinct MI355X has more VRAM (288GB).
Is Hopper H200 SXM or Instinct MI355X better for LLM training?+
For LLM training at scale, the Instinct MI355X has higher raw throughput. However, the choice also depends on your software stack: Hopper H200 SXM offers CUDA compatibility with the widest framework support (PyTorch, JAX, TensorRT).
What is the price difference between Hopper H200 SXM and Instinct MI355X?+
The Hopper H200 SXM is estimated at $30,000 per unit and the Instinct MI355X at $30,000. Actual pricing varies by vendor, volume, and configuration. Check our Buy page for current reseller pricing.
Which GPU is more power efficient, Hopper H200 SXM or Instinct MI355X?+
The Hopper H200 SXM has a lower TDP (700W vs 1400W). Performance-per-watt depends on your workload — for FP8 inference, divide TFLOPS by TDP: Hopper H200 SXM = 5.7 TFLOPS/W vs Instinct MI355X = 3.3 TFLOPS/W.